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Impact of linker structure design on the release efficiency of MMAE In order to improve ADCs efficacy, one method is to avoid or reduce drug resistance of the payload

Key Takeaway Glutathione is the bodys primary antioxidant, helping to support detoxification, immune function and protection against oxidative stress

The brain uses it to protect neurons

Elevated GSH levels are observed in various types of tumors, and this makes the neoplastic tissues more resistant to chemotherapy [10, 11]

The literature still lacks consensus on the optimal balance between sensitivity and signal stability, making cross-study interpretation difficult

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