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Emphasizing the negative effect on male reproductive health, a systematic review and meta-analysis found that exposure to phthalates and their metabolites is linked to a decrease in sperm quality (84)

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doi: 10.1111/bdi.12159 64 SeveranceEGPrandovszkyECastiglioneJYolkenRH

The mechanisms proposed are consistent across organ systems: reduced oxidative stress, modulation of inflammatory cytokine cascades, and support for local microcirculation through angiogenic activity

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