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et Zucc., Salvia miltiorrhiza Bunge., Artemisia capillaris Thunb., and Nelumbo nucifera Gaert.], and Cassiae Semen, as well as NPs, such as Berberine and Gynostemma, have been reported to improve NAFLD by regulating the gut microbiota, which provides a promising strategy and direction for NAFLD research and therapy (67)

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Large-scale clinical trials, such as the SUSTAIN-6 trial, found that semaglutide significantly reduced the risk of major adverse cardiovascular events (MACE), including heart attacks and strokes, in people with type 2 diabetes and high cardiovascular risk