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While ETC is the source of superoxide, the existence of mitochondrial NO synthase (mtNOS) that provides the NO required to form peroxynitrite is controversial

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A different plant-derived substance that according to recent studies has therapeutic potential in RA is taraxasterol (TAR), one of the bioactive pentacyclic triterpenes isolated from Taraxacum officinale

All other relevant data are available from the corresponding author on request

After 10 min of administration, the total radioactivity concentration increased significantly in all tissues, with the mean renal tissue concentration reaching 223 ng (Eq