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On the other hand, peptides tied to more aggressive metabolic effects, or those requiring a larger dose to be effective, such as Tesamorelin, tend to come with a slightly higher chance of water retention or joint discomfort in the early weeks, simply because of how strongly they influence growth hormone output
J Pain Symptom Manage
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10.1097/MED.0b013e32835edb32 [DOI] [PubMed] [Google Scholar] 232.Kawai T, Sun B, Yoshino H, Feng D, Suzuki Y, Fukazawa M, et al
They are expressed in salivary gland tissue