Graphical Abstract Keywords Acetaminophen, Caspase-1, Drug-induced liver injury, Inflammasome, NOD-, LRR-, and pyrin domain-containing 3, NLRP3 Introduction Acetaminophen (APAP), commonly known as paracetamol, is a widely used over-the-counter medication renowned for its analgesic and antipyretic properties
While in vitro studies and animal models have provided positive indications, it is crucial to validate these findings in human subjects to establish the relevance and applicability of A1AT augmentation treatment
The N -acetylation of the Cys S -conjugates of the sevoflurane degradation products 287 and 289 ( N -acetylation, respectively (Altuntas and Kharasch Citation2002)
G6PD Deficiency Triggers G6PD deficiency is a genetic condition that results from gene mutations
Antioxidant therapy represents a promising intervention to mitigate the harmful effects of ROS on reproductive health in additions to its easy accessibility, safety, and low cost
Human glutathione S -transferase-mediated glutathione conjugation of curcumin and efflux of these conjugates in Caco-2 cells