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The most common ones seen in studies include: Nausea Vomiting Diarrhea Constipation Abdominal discomfort Less common or study-observed effects have included: Transient increases in resting heart rate Mild liver-enzyme changes Injection-site reactions Questions Researchers Are Still Studying Long-term cardiovascular outcomes The balance between fat loss and lean-mass loss Long-term metabolic maintenance Ideal dosing strategies How retatrutide performs across different health backgrounds Because research is ongoing, these areas will continue to be refined over time

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If you experience severe vomiting or diarrhoea or are unable to maintain adequate hydration, seek clinical advice promptly

Semaglutide is not a magic pill, says Dr Winnett

In addition, she had a fairly low Th2 phenotype, with a low blood eosinophil count (BEC) and fractional exhaled nitric oxide (FENO) even at the height of her symptoms, which may be a more difficult phenotype of asthmatic to treat effectively

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