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Mol Metab 2021;46:101102

In 2017 the U.S

Sources/Disclosures Source: Press Release Disclosures: Healio could not determine relevant financial disclosures at the time of publication

Direct answer: Mild digestive symptoms like nausea, constipation, or bloating may continue but often improve in severity

If youre using GLP-1s for diabetes: Combination therapy using insulin or sulfonylureas alongside GLP-1s increases your risk Timing clashes when two medications lower your blood sugar at the same time Dose adjustments without matching changes in your food intake If youre using GLP-1s for weight loss only: Skipping meals or eating very little throughout the day Low-carb or restrictive diets that dont provide steady energy Delayed digestion, which slows the release of glucose into your system Increased exercise without adjusting what or when you eat Other contributing factors include: Kidney or liver problems, which affect glucose balance Recent illness, infection, or stress Alcohol consumption Certain non-diabetes medications that affect blood sugar How to Manage Low Blood Sugar on GLP-1s If youre at risk of hypoglycaemia, or youve already experienced symptoms, there are simple steps you can take to prevent and manage it

Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide-1 receptor activation