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2001 Jul 15;61(14):5378-81

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can cause glutathione to be used at an excessive rate, leading to depletion

They studied peripheral vascular function, hepatic function, lipid profile and oxidative stress on the subjects after four weeks of treatment

developed biodegradable nanocomposite microspheres encapsulating DFP to enhance mucoadhesion and sustain drug release for nasal administration ( in vitro and in vivo efficacy data are still lacking