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L- (IBS)

In most cases, lip pigmentation is caused by repeated irritation, sun damage, dryness or reduced blood circulation

The GH/IGF-1 axis is highly sensitive to small changes in GH or IGF-1 2 levels, which can trigger feedback suppression or amplify downstream effects

Finally, restrain-free production run was carried out for each simulation, with a time step of 2 fs in the NPT ensemble at 310 K and 1 bar using the Nose-Hoover thermostat and the semi-isotropic Parrinello-Rahman barostat 61 , respectively