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Hyperseborrhea can result from hormonal factors, notably an increased sensitivity of the sebaceous glands to androgens, as well as from genetic predispositions, disturbances in the skin microbiota, or environmental factors

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In patients with moderate hepatic impairment (Child-Pugh score 7 - 9), the maximum recommended dosage is QSYMIA 7.5 mg/46 mg orally once daily

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