In vivo , intra-articular injection of FN-CNPs in DMM mice slows OA progression and preserves cartilage integrity by modulating ROS levels, antioxidant defense, and lipid metabolism
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Thus, the photoperiod signal is transformed into changes in melatonin content in the animal, thereby regulating the reproductive cycle of animals with seasonal estrus (69, 70)
To measure PIP 3 , FoB were stimulated with 5 g/mL anti-IgM (Jackson Immunoresearch 715-006-020) for the indicated time points, then fixed in 2% FA and permeabilized with 0.1% saponin
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