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Ann Rheum Dis (2018) 77(11):163643

This aspect is especially valuable for individuals at risk of or currently facing neurodegenerative diseases like Alzheimers and Parkinsons

NADPH, one product of the G6PD reaction, is a potent quasicompetitive inhibitor, and because most of the coenzyme in cells is in the reduced form, it can be assumed that G6PD is normally under strong inhibition

Camel milk as a potential therapy as an antioxidant in autism spectrum disorder (ASD)

Such biomarkers must be validated in large clinical cohorts to determine their utility for early diagnosis, risk stratification, predicting therapeutic response, and monitoring efficacy (Rosenblatt et al., 2025)

The mechanistic rationale builds on earlier work by Kraus and colleagues in Nature (2014), in which adipocyte-specific NNMT knockdown protected mice from diet-induced obesity, establishing NNMT as a metabolic-disease target candidate [2]