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Efecto pleiotrpico de arGLP-1

The effect of such combination therapy on heart and kidney outcomes in DKD is unknown, though it is conceivable that additive benefits on weight loss and blood pressure would confer additive benefits on harder clinical outcomes (Table 1)

The most frequently reported side effects of tirzepatide are gastrointestinal in nature, consistent with the drug class mechanism of slowing gastric emptying