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Description

5-Amino-1MQ is an Nicotinamide N-methyltransferase (NNMT) inhibitor that has been shown to reverse diet-induced obesity

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Philp and colleagues (FASEB J, 2003) showed the LKKTETQ site alone is sufficient to promote endothelial cell migration and angiogenesis in aortic ring and chick chorioallantoic assays, and Sosne and colleagues (FASEB J, 2010) mapped further activities onto short internal sequences of the parent protein

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