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As expected, the GSH levels were reduced by 100 M of hydrogen peroxide but enhancing network activity with blockers of GABA A receptors (bicuculine) and KCNA channels (4-AP) attenuated this effect

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Furthermore, at 15 weeks, analysis of striatal tissues from Gsto2 -shRNA-injected mutants showed significant rescue of SST and NPY immunoreactive neuron numbers compared with mutants injected with scrambled shRNA and control mice (Fig