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48 children (ages ~312) were randomized to leucovorin (2 mg/kg per day, max 50 mg, split twice daily) or placebo

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Key points Personalized medical nutrition therapy is a cornerstone of type 2 diabetes mellitus (T2DM) management, with evidence supporting its role in improving glycaemic control and insulin sensitivity and in reducing diabetes mellitus-related complications in individuals both with and without obesity

Self-insured employer plans (covering about 65% of commercially insured Americans) can choose to exclude anti-obesity medications, and many do to control costs