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Curr Medicinal Chem (2014) 21:1595606

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In studies, participants receiving higher retatrutide doses achieved average weight reductions approaching or exceeding 24% of their starting body weight

Animal Model:8-10 male C57BL/6J mice [1] Dosage:50 mg/kg Administration:i.p., a single dose for 28 or 12 days Result:Displayed a more oxidative muscle phenotype, increased the complex I (NDUFB8) and complex V (ATP5A) protein expression in the gastrocnemius muscle and cytochrome C, mitochondria content and oxidative type IIa muscle fibers lavels in mice