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Tu C, Lu H, Zhou T, Zhang W, Deng L, Cao W, et al

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Natural bioactive compounds Plant extracts, spices, herbs, and essential oils all include natural ingredients that have shown promise in treating MetS

Critical limitations include: Heterogeneity : Different strains, doses, and formulations make comparisons difficult Small effect sizes : Weight changes are typically modest and may not be clinically significant Short duration : Most studies last 12 weeks or less, providing no data on sustained effects Publication bias : Negative studies may be underreported There is no high-quality evidence that probiotic supplements can replicate the substantial weight loss achieved with prescription medications like semaglutide or tirzepatide

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2023 Jun 29