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This minimises shear forces and reduces air bubble formation, both of which promote aggregation

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2 Classification and mechanisms of AMPs 2.1 Thionins 2.1.1 Family and structure Thionins are a major class of plant-derived antimicrobial peptides (AMPs), alongside defensins, non-specific lipid transfer proteins, hevein-like peptides, knottin-like peptides, and cyclotides, distinguished by their cysteine spacing motifs and three-dimensional (3D) structures (Odintsova et al., 2018)

Recent studies have highlighted the critical role of inflammation in stone disease models and in the kidney tissues of individuals with nephrolithiasis [38]

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Thus, the reduced form glutathione is stable under this condition and also matrix effect on ionization can be neglected