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GLP-1 receptor agonists are licensed for type 2 diabetes and weight management, not menopausal symptoms These medications work by enhancing insulin secretion, suppressing glucagon, slowing gastric emptying, and reducing appetite Weight loss from GLP-1 therapy may theoretically influence vasomotor symptoms, but robust clinical trial evidence is lacking Hormone replacement therapy remains the most effective first-line treatment for moderate to severe hot flashes in the UK Common GLP-1 side effects include gastrointestinal symptoms, with risks of pancreatitis and gallbladder disease requiring monitoring Table of Contents What Are GLP-1 Medications and How Do They Work
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[] A study by Ayala [] , reported a novel insight into the spatiotemporal dynamics of GLP-1R and GIPR modification and signaling in INS-1-832/3 -cell line and primary cells of islets
Rash or irritation at the injection site: Irritation from the medication or preservatives can cause injection site redness, pain, or swelling
After reaching a plateau around week 40 to 44, participants maintained their weight through week 48 with minimal regain of only 0.8kg on average
