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Overall, findings from high-income countries show that DHA status differs across dietary patterns and levels of fish consumption, highlighting the potential role of food availability and dietary context in shaping cross-country differences

Additionally, NAD + is required for fatty acid metabolism during -oxidation, glutaminolysis generating -ketoglutarate, mitochondrial shuttling of metabolites, and lactic acid fermentation 3,4,5

The first and rate-limiting step is catalyzed by an enzyme called glutamate-cysteine ligase (GCL), which links glutamate and cysteine together

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