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Keep records of batch numbers and purchase dates

Research interest in epithalon centers on its reported interaction with telomerase-related mechanisms in in vitro cell senescence models, its effects on pineal gland peptide receptor systems in preclinical experiments, and its behavior in circadian rhythm-related gene expression studies in controlled cell culture settings

Blind cage coding and automated video analysis (EthoVision, TopScan) are recommended Too low n : prior power analysis, n 8 minimum for rodent behavioural tests No positive control : without memantine, donepezil or scopolamine depending on the paradigm, impossible to judge if the model is functional No dose-response : a single tested dose is insufficient to conclude

However, it is not clear whether FMT is a transient improvement or an improvement of the underlying cause, and the long-term safety of FMT treatment must also be verified [319]

& Zhou, W

Acknowledgements: The authors express their gratitude to Gabor Tornyai for his excellent technical help