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Oral administration has the benefit of high patient compliance and has demonstrated the potential to target brain iron pathology, especially with BBB-permeant agents like DFP

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That is part of why glutathione nasal spray attracts interest for neurological and cognitive applications

Given the importance of hyperandrogenism-hyperinsulinemia in PCOS, most of the current therapeutic strategies aim at reducing androgen excess by improving insulin sensitivity, mainly via lifestyle changes and/or pharmacological approaches