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Large and symptomatic nodules or goiters can be treated with surgery when the more conservative approaches have proven fruitless

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All the mice in the five groups yielded similar serum creatinine levels

HPLC separation was performed using a Phenomenex Kinetex F5 (100 2.1 mm, 2.6 m) (Phenomenex Inc., CA, USA) at a flow rate of 0.2 mL/min, with the column temperature maintained at 40 C using an Agilent column thermostat

10.1007/s00404-018-4861-y 45 LanK