is itching a side effect of semaglutide Top 5 Common Effects and How to Minimize Them Dermal Hypersensitivity Reaction to Semaglutide:

In the overall STEP program, nearly 10% of participants without diabetes and more than 30% of participants with type 2 diabetes experienced less than 5% weight loss, despite use of a potent GLP-1 receptor agonist plus lifestyle intervention

Beyond pancreatic effects, GLP-1 slows gastric emptying, which moderates postprandial glucose excursions, and acts on central nervous system receptors to promote satiety and reduce appetite

Postgraduate Medicine, 134(1), 1419

How long does it take to reach maximum weight loss on semaglutide

This extended presence influences clinical decisions around surgery, switching medications, and discontinuation strategies

Though not FDA-approved for weight loss, it is used off-label to reduce stubborn fat