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Blood (2003) 102(13):44938

Abstract Nitrogen detoxification pathways in the central nervous system supply a range of neurotransmitters, ranging from long-appreciated examples like nitric oxide and agmatine, to emergent neurotransmitters including spermidine, spermine, and polyamine-derived GABA

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Compression leads to numbness, tingling, weakness, and that distinctive nighttime discomfort many sufferers report