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doi:10.1017/S1461145713001685 McCoy, Alene T et al

Our study identified a marked increase in S100a4+ macrophages, originating from monocytes, strongly associated with fibrotic changes

"These drugs have the potential to bring about substantial weight loss, particularly in the first year," says Juan Franco, co-lead researcher from Heinrich Heine University Dsseldorf, Germany

Notably, previous meta-analyses have been inconsistent, and no further meta-analyses have been published in the last 5 years

At present, more than half a billion population are living with diabetes globally

Commonly used agents for the treatment of melasma include hydroquinone, azelaic acid, kojic acid, glycolic acid, salicylic acid, and tretinoin