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Long-term data from a 52-week clinical study found that escitalopram reduced relapse risk by 2.8 times compared with placebo, with 22% of escitalopram-treated patients relapsing versus 50% on placebo, supporting maintenance treatment after improvement, according to this 52-week social anxiety relapse-prevention study on PubMed

Yes, it is generally safe to take L-cysteine or NAC daily at recommended doses (usually 600-1,200 mg/day for NAC), but long-term use should be monitored by a healthcare provider, especially if you have kidney or liver conditions

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The drug was developed in the 1940s by Albert Hofmann [138], and thus, is one of the oldest nootropic drugs still in use

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GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition