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Distinguishing from Other Spots: Sometimes, it can be hard to tell the difference between a harmless freckle and a more concerning spot like a mole or a sunspot that could potentially be cancerous

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In ACLF, HE is more frequent in younger patients with more severe liver failure, infection and evidence of systemic inflammation (white cell count and C-reactive protein)

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Gastroenterology 139 , 456463 (2010)

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