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4,12 Four agentsalendronate, risedronate, zoledronic acid, and denosumabhave evidence for broad spectrum anti-fracture efficacy and are considered initial options in most cases

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it may take longer to reach the target of below 7% if your initial levels are very high

0.6-0.8% placebo), consistent with the rapid weight loss effect Thyroid C-cell tumors : As with all GLP-1R agonists, tirzepatide carries a boxed warning based on rodent thyroid C-cell tumor findings

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Mix half a scoop in extra water when your appetite is low, then use a full scoop when you need a stronger protein bump