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When Sterile Water Is the Better Choice There are specific situations where sterile water is not just acceptable but preferable

During the initial treatment phase, your body begins the process of rebuilding B12 stores in the liver, which can take several weeks to months depending on the degree of depletion

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For many individuals, oral B12 supplements are ineffective due to such underlying conditions as: Pernicious anemia : People with this condition lack intrinsic factor, a protein required for B12 absorption in the small intestine

Therapeutic benefits are more cumulative, making it effective for sustained vitamin B12 levels over time

Gastroenterology 119 , 10291036 (2000)