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While they occasionally offer "introductory" promotions (such as $223 for the first month), the long-term maintenance cost remains very high due to the dual-billing structure

If tolerability issues arise with the combination, healthcare providers might consider temporarily pausing dose escalation, using 1.7 mg as a maintenance dose if 2.4 mg is not tolerated, adjusting Prozac timing (e.g., taking with food), or implementing supportive measures

It does not increase thermogenesis (heat production) or significantly elevate resting energy expenditure in humans

fda.gov Wilding JPH, Batterham RL, Calanna S, et al

"Our findings should be viewed as being significant but tentative, as future studies are needed to examine these questions in a much larger and more diverse population, said Rizzo