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Some individuals may experience mild digestive discomfort, especially when first starting the supplement

- **Treatment history**: Records should note an unsatisfactory response to oral iron therapy or intolerance, as well as whether the patient requires supplemental iron to maintain iron balance

First, whether doses larger than 2.88 mg/kg would further improve MWM performance is worth exploring in future studies

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The model is also consistent with published results that show that female mice are less susceptible than males to hepatotoxicity due to acetaminophen overdose and suggests that this might also be true for humans, though the human epidemiological data are contradictory