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Cerebral organoids offer a more promising platform for studying chronic neurodegeneration

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Western blotting revealed that knocking down CYPOR prevented Nrf2 accumulation and GCLC induction upon NFT treatment (Fig

de Keizer Published: 2017 March Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells Senescent cells accumulate in tissues over time as part of the natural ageing process and the removal of senescent cells has shown promise for alleviating many different age-related diseases in mice

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However, the trial outcome was encouraging, with good patient tolerability [95]