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Wilson Disease levels help separate Wilson disease Wilson disease Wilson disease (hepatolenticular degeneration) is an autosomal recessive disorder caused by various mutations in the ATP7B gene, which regulates copper transport within hepatocytes

Evaluation of molecular chaperons Hsp72 and neuropeptide Y as characteristic markers of adaptogenic activity of plant extracts

PLoS Computat

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Their therapeutic action is predicated on a confluence of mechanisms, including increased nitric oxide (NO) bioavailability, reduced oxidative stress, and the intricate modulation of vasoactive signaling cascades

Consequently, a decrease in Cu availability in these cells due to a decrease in metallothionein production and Cu uptake in the intestine would result in a decrease in dopamine degradation by the MAO pathway, since the activity of this enzyme is Cu-dependent (129, 154)