The crude product was purified by a silica gel column chromatography using hexane and dichloromethane mixture (10:1 v/v) as eluent and obtained as yellow powder in 74% yield
of Cancer 29A(4):638-45
In summary, a comprehensive analysis of 19 kinase candidates, which integrated LC-MS/MS data from several co-immunoprecipitations, in silico modeling, RNAi screening, and consensus sequence validation, identified KIN-19 as the most promising kinase candidate for further investigation
Furthermore, fasting-induced fluctuations in lipid metabolism genes were restored upon refeeding
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Once these cis-acting regulatory elements are identified, the transcription factor proteins required for transcriptional activation can be also determined