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Moreover, this neurochemical imbalance, as hypothesised, was also related to a measure of habitual responding versus goal-directed control over behaviour in these regions, relevant to theories proposing that this bias underlies compulsive behaviour in clinical disorders of obsessive-compulsive disorder and drug addiction 3,32

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Vitamin E: regulatory role on signal transduction

Melatonin efficiently interacts with various reactive oxygen and reactive nitrogen species (receptor independent actions) and it also upregulates antioxidant enzymes and downregulates pro-oxidant enzymes (receptor-dependent actions)

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