J Circadian Rhythms
The H 2 O 2 generated by Mn-SOD can be removed by glutathione peroxidase in the mitochondria or, if it diffuses into the cytosol, H 2 O 2 can be removed by cytosolic antioxidants, such as catalase (CAT), and peroxiredoxins (Prx), that act in conjunction with SOD
Dry Mouth, Bad Breath and Tooth Damage: The Effects Ozempic and Wegovy Can Have on Your Mouth
Sean Hashmi, MD, is the regional medical director of Lifestyle & Obesity Medicine for the Southern California Permanente Medical Group, and national chair of the interregional clinical practice group for Lifestyle & Obesity Medicine, The Permanente Federation.
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Early studies suggest that GLP-1s may enhance dopamine signalling and reduce neuroinflammation, which could improve motivation and resilience, as stronger dopamine signalling means less fatigue and better motivation, and reduced neuroinflammation supports mental clarity