Roughly a quarter to 40 percent of weight lost on GLP-1s can come from lean mass depending on study and population
J Mol Biol 432: 1347-1366, 2020
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Combined with the theory of GIP being an obesogenic hormone (53), these prior findings have highlighted the potential of GIP receptor antagonism, and today the development of GIP receptor antagonists has also emerged as an attractive therapeutic approach for addressing obesity and cardiovascular diseases (54, 55)
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(Neural Regen Res, 2022), Cushman et al