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3g), but the H 2 O 2 -inhibition efficiency of ZMTP is much lower than that of natural catalase, as in catalase the oxoferryl porphyrin cation radical (P + -Fe IV = O) (rather than Fe V ) can form under the assistance of Tyr 354 residue, which favors the valence transition of Fe center during H 2 O 2 decomposition

The pathogenesis of various liver diseases, including ALF, has implicated GSH depletion

Significance testing was done using one way ANOVA

Denolly, S

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