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Postmenopausal bone loss accelerates in the first 35 years after menopause precisely the window where HRT has the most protective effect on bone mineral density

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Moreover, IGF-1 knock-out mice exhibited significantly reduced expression of FSH receptors and consequently reduced aromatase expression and E2 secretion (68), indicating that IGF-signaling may regulate gonadotropin receptor expression

Compared with insulin, GLP-1 use during pregnancy didnt increase the risk of major birth or heart defects

Plasma levels of glutamate during stroke is associated with development of post-stroke depression

STEP 2 (Obesity with Diabetes): In adults with both obesity and type 2 diabetes, a population known to have more difficulty losing weight, Wegovy still produced a mean weight loss of 9.6%, compared to just 3.4% with placebo