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GHRH (e.g., CJC-1295, Tesamorelin) stimulates pituitary somatotroph cells via the GHRH-R receptor, increasing the amplitude of each GH pulse

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These findings point to possible GH-mediated activity on osteoblast proliferation and differentiation

Petralito A, Lunetta M, Liuzzo A, Mangiafico RA, Fiore CE

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