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Current recommendations for muscle preservation during weight loss range from 1.2-2.0g protein per kilogram of body weight daily, with higher intake better for preserving lean mass

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However, higher doses extend the duration of receptor occupancy and downstream signaling because more peptide molecules are available to bind receptors over the clearance window

Lets be perfectly clear from the outset: Accutane (the brand name for the drug Isotretinoin) is not a weight loss medication