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DOI: Published: Publisher Name: Springer, Singapore Print ISBN: 978-981-95-0436-7 Online ISBN: 978-981-95-0437-4 eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)

37 The activation of specific membrane receptors triggers the differentiation of nave T cells into effector T cells, also known as T eff cells

135 , 247278 (2012) Jazayeri, A

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Nonetheless, certain critical limitations of MSC-based therapy remain and need to be overcome before widespread clinical application becomes possible [5]