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Early and laterstage persistence with anti-obesity medications: A retrospective cohort study

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Phentermine-topiramate ( Qsymia ): Constipation happens in 8%16% of people on Qsymia, depending on the dose

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Malnutrition requiring hospitalization

Be alert to symptoms that may indicate thyroid dysfunction , such as: Worsening fatigue, cold intolerance, or constipation (suggesting under-replacement) Palpitations, anxiety, tremor, or heat intolerance (suggesting over-replacement) A lump or swelling in the neck, hoarseness, or difficulty swallowing (which should prompt urgent evaluation according to NICE guideline NG12) [9] [10] Whilst there is no evidence that Wegovy causes thyroid dysfunction in humans , you should report any new or unusual neck symptoms to your GP immediately