Inhibition of the Xc-system determines the decrease in GSH levels, which indirectly leads to the inactivation of GPX4 and the onset of ferroptosis (Ursini and Maiorino, 2020)
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Thus, the concentrations used in the in vitro and in vivo investigations were determined according to the GSH levels present in the YE
He has participated in Advisory Board with AstraZeneca, and Boheringer Ingelheim