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The main function of NLRP3 inflammasome is an activation of caspase-1, maturation of IL-1 and IL-18 (He et al

In the present study, we extend these findings by showing livers from GCLM KO mice exhibit a persistently greater level of oxidant stress as measured by protein carbonylation and expression of redox-sensitive genes

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276,277 Other prospective cohort studies have revealed the associations between prudent diets (rich in whole grains and dietary fiber) and Western diets (rich in red and processed meat, refined grains, and desserts) with CRC risk and indicated that the effect of these diets may differ based on the presence of Fusobacterium nucleatum in tumor tissue