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They recapitulate many aspects of the native tissues and are valuable models for modelling human genetics and disease mechanisms and for drug screening

J Biol Chem 267:1522415228 Vartanyan LS, Gurevich S, Kozachenko AI, Nagler LG, Lozovskaya EL, Burlakova EB (2000) Changes in superoxide production rate and in superoxide dismutase and glutathione peroxidase activities in subcellular organelles in mouse liver under exposure to low doses of low-intensity radiation