If you arent completely confident in your ability or feel worried, a safe choice may be to schedule an appointment to have it administered by a physician in their clinic, or to have your B12 shot administered at a pharmacy
[95] Intramuscular or intravenous injection [edit] Injection of hydroxycobalamin is often used if digestive absorption is impaired, [2] but this course of action may not be necessary with high-dose oral supplements (such as 0.51.0 mg or more), [97] [98] because with large quantities of the vitamin taken orally, even the 1% to 5% of free crystalline B 12 that is absorbed along the entire intestine by passive diffusion may be sufficient to provide a necessary amount
A large proportion of participants exhibited hormonal imbalances, with one-fourth of participants having elevated FSH, one-third elevated LH, and 74.9% increased estradiol

Food & Drug Administration (2025) Ozempic, DailyMed (2025) Wegovy, DailyMed (2024) Once-weekly semaglutide in adults with overweight or obesity, New England Journal of Medicine (2021) Vitamin B12, National Institutes of Health Office of Dietary Supplements (2024) Vitamin B12 injections: What they can and cant do, Cleveland Clinic (2024) Once-weekly semaglutide administered after laparoscopic sleeve gastrectomy: Effects on body weight, glycemic control, and measured nutritional metrics in Japanese patients having both obesity and type 2 diabetes, Obesity Pillars (2024) Inverse association between serum vitamin B12 concentration and obesity among adults in the United States, Frontiers in Endocrinology (Lausanne) (2019) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice
The staff is professional, knowledgeable, and truly cares about your goals
If youre feeling sluggish or finding it tough to stay active, B12 injections for weight loss could help boost your energy levels